Sunday 24 August 2008

Swedish Diabetics Experience Decline In Stroke Incidence

�The incidence of strokes among diabetics in Northern Sweden declined between 1985 and 2003, according to a population-based study published in Stroke: Journal of the American Heart Association.



Researchers also institute that endurance rates improved leading to a rapid decline in the number of disastrous events among diabetic people.



"Prior research has suggested that the vogue in strokes was increasing, but our study shows declining incidence in stroke for non-diabetic men, both for low and recurrent stroke, and in perennial strokes in non-diabetic women," said Mats Eliasson, M.D., Ph.D., joint author of the study and a senior lecturer in the Department of Public Health and Clinical Medicine at Ume� University and the Department of Medicine at Sunderby Hospital in Lule� Sweden.



The reasons for the overall decline of strokes among diabetics are uncertain. The decline may be the result of more intensive treatment of hypertension in diabetics and smoking cessation and cholesterol-lowering efforts, Eliasson said.



"The telling decline in smoking and large decreases in cholesterol levels, and to a lesser degree blood pressure levels, in the population of northern Sweden may have contributed to the declining incidence in both diabetic and non-diabetic subjects over the study period," he aforesaid. "On the other hand, we found more recurrent events among diabetic subjects than non-diabetic subjects, indicating a want for regular more intensive secondary bar among diabetic patients."



Researchers examined data on 15,382 stroke patients, 35- to 74-years-old, wHO were piece of the Northern Sweden MONICA (Multinational Monitoring of Trends and Determinants in Cardiovascular Disease) Project Stroke Registry, an international collaboration sponsored by the World Health Organization.



Over the 19 years, 11,605 subjects suffered a first stroke and 3,777 had a perennial stroke. Twenty-two percent of the workforce and women had antecedently been diagnosed with diabetes. Although the total identification number of strokes per one C,000 in diabetics was significantly greater than in non-diabetics, researchers found no significant difference in the rate of decline over time and death rates between the two groups.



Among the major findings:
Diabetic women had a annual decrease in incidence of first-ever stroke of 1.5 percentage, while relative incidence remained unchanged over the observation period for non-diabetic women.



Non-diabetic men had a significant declining trend in relative incidence rates of first-ever cVA of .8 percent per year, piece there was an insignificant decline in diabetic work force.



All groups, except diabetic women with first-ever slash, had a significant decline in deaths over time.



Incidence rates per century,000 of all strokes among male diabetics fell from 1,961 to 1,815.



The incidence rates per 100,000 of all stroke in women fell from 1,921 to 1,176.



In non-diabetics, the incidence rates per 100,000 fell from 358 for men and 204 for women to 284 and 183, severally.



For perennial strokes, the decline was significant for all simply diabetic work force, with the greatest decline (5.4 percent a year) in diabetic women. Non-diabetic women showed a 2.7 percent yearbook drop. Researchers found no apparent account for the gender differences. An sooner study in the United States didn't find sexuality differences in care or treatment bond between male and female diabetics.


"The fact that patients with diabetes, to a with child extent, had favorable time trends similar to those of non-diabetics is specially interesting considering that diabetic patients with heart attempt, from the same population, did not show whatsoever positive trends over the 19-year study," Eliasson said.



Control of high blood pressure may have a greater impact in stroke than in coronary thrombosis heart disease, he said.





Co-authors are Aslak Rautio, M.D., and Birgitta Stegmayr, Ph.D. Individual source disclosures commode be establish on the manuscript.


For more information on stroke, visit the American Stroke Association Web land site: http://www.strokeassociation.org/.



Statements and conclusions of study authors published in American Heart Association scientific journals ar solely those of the study authors and do not needs reflect the association's policy or position. The association makes no representation or guarantee as to their accuracy or reliability. The association receives funding primarily from individuals; foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific association programs and events. The association has strict policies to prevent these relationships from influencing the science subject. Revenues from pharmaceutical and device corporations are available at http://www.americanheart.org/corporatefunding.



Source: Bridgette McNeill

American Heart Association



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